Yes, our source of melatonin is 100% natural and plant-derived! It comes from St. John’s Wort (Hypericum perforatum L.), which is a perennial flowering plant that grows all over the world. In fact, it’s considered a weed in many parts of the world. St. John’s Wort has been used for centuries in traditional medicine for minor burns, anxiety, and mild to moderate depression. You can read more about St. John’s Wort here.