Is it possible to over-use Mella products? How much is too much? June 19, 2021 00:13 Updated No need to worry -- even at much higher doses (topical and ingested) than we use in Mella products (even higher than in a full daily Mella routine), melatonin has been proven safe. Related articles Citations for "Melatonin Outperforms Vitamin C" Has melatonin been studied in topical use? Where is proof that it has all these benefits?